Syphilis: Causes, Symptoms, Stages, and Effective Treatment

The word "Syphilis" written in medical style on a clean background.


🧬 What is Syphilis?

Syphilis is a sexually transmitted infection (STI) caused by the bacterium Treponema pallidum. If left untreated, it can lead to serious and long-term health problems.

It develops in four stages:

Primary → Secondary → Latent → Tertiary

Each stage has its own signs and symptoms. Also, babies can be infected during pregnancy — a condition known as congenital syphilis.


⚠️ Signs and Symptoms

1️⃣ Primary Stage

  • Appears as one or more painless sores (chancres) on:
    • Penis, vagina, anus, rectum, lips, or mouth.
  • Sores heal in 3–6 weeks even without treatment, but treatment is necessary to prevent disease progression.

2️⃣ Secondary Stage

  • Characterized by skin rashes (often on palms and soles) and/or sores in the mouth, vagina, or anus.
  • The rash is bumpy, red or red-brown, and does not itch.

Other symptoms include:

  • Fever
  • Swollen lymph nodes
  • Sore throat
  • Hair loss
  • Headache
  • Weight loss
  • Muscle aches
  • Fatigue
Symptoms may disappear on their own, but infection remains (latent stage).

3️⃣ Latent Stage

  • No visible symptoms, but bacteria remain in the body.
  • The infection can stay dormant for years if untreated.

4️⃣ Tertiary Stage

  • Occurs in untreated cases 10–30 years later.
  • Can damage the:
    • Heart
    • Blood vessels
    • Brain and nerves
  • May lead to death.
  • May cause gummas (destructive ulcers) or nerve/heart damage.

🧠 Special Forms

  • Neurosyphilis: affects brain and nerves → causes confusion, weakness, memory loss.
  • Ocular syphilis: affects eyes → pain, redness, vision changes, or blindness.
  • Otosyphilis: affects ears → hearing loss, tinnitus, or vertigo.

🔄 Transmission

  • Spread through direct contact with syphilis sores during:
    • Vaginal, anal, or oral sex
  • Can also pass from mother to baby during pregnancy.

Not spread by:

  • Toilet seats
  • Clothing
  • Eating utensils
  • Swimming pools

🛡️ Prevention

  • Avoid sexual contact when infected.
  • Always use condoms correctly, but remember sores outside condom-covered areas can still transmit infection.
  • Have sex only with a tested, faithful partner.
  • Pregnant women should get tested early and treated immediately if positive.

👶 Congenital Syphilis

  • Transmission from infected mother to newborn.
  • Can cause:
    • Low birth weight
    • Premature birth
    • Stillbirth
    • Serious defects (deafness, cataracts, seizures)

🔬 Diagnosis

  • Done through blood tests or examination of lesion fluid.
  • All pregnant women should be tested during their first prenatal visit — and again later if needed.

💊 Treatment and Recovery

  • Penicillin is the treatment of choice.
  • Treatment stops further damage, but cannot reverse existing organ damage.
  • Even after successful treatment, reinfection is possible.
  • Follow-up tests and treating sexual partners are essential.

📚 Sources / References

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